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fosfomycin biosynthesis

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
(S)-2-hydroxypropylphosphonate + H2O2 <=> fosfomycin + H2O 1.11.1.23 (S)-2-hydroxypropylphosphonic acid epoxidase

S-adenosyl-L-methionine + cytidine_5''-{[hydroxy(2-hydroxyethyl)phosphonoyl]phosphate} + reduced_acceptor <=> 5''-deoxyadenosine + L-methionine + S-adenosyl-L-homocysteine + cytidine_5''-{[hydroxy(2-hydroxypropyl)phosphonoyl]phosphate} + acceptor + H+ 2.1.1.308 cytidylyl-2-hydroxyethylphosphonate methyltransferase

CTP + 2-hydroxyethylphosphonate <=> cytidine_5''-{[hydroxy(2-hydroxyethyl)phosphonoyl]phosphate} + diphosphate 2.7.7.104 2-hydroxyethylphosphonate cytidylyltransferase

H+ + Phosphonopyruvate <=> phosphonoacetaldehyde + CO2 4.1.1.82 phosphonopyruvate decarboxylase

2-hydroxyethylphosphonate + NAD+ <=> phosphonoacetaldehyde + NADH + H+ 1.1.1.309 phosphonoacetaldehyde reductase (NADH)

cytidine_5''-{[hydroxy(2-hydroxypropyl)phosphonoyl]phosphate} + H2O <=> (S)-2-hydroxypropylphosphonate + CMP + H+ 3.6.1

H+ + phosphoenolpyruvate <=> Phosphonopyruvate 5.4.2.9 phosphoenolpyruvate mutase

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